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Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)

Funding
Up to $150,000
Status
Open
Deadline
August 11, 2027
Agency
Scope
Nationwide
Source
Grants.gov
Up to $150K
August 11, 2027
Nationwide

Description

The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innovative or conceptually creative research related to the etiology, pathophysiology, prevention, or treatment of substance use disorders (SUDs). It supports high-risk and potentially high-impact research that is sparse or not included in NIDA's current portfolio that has the potential to transform SUD research. The proposed research should: 1. develop, and/or adapt, revolutionary techniques or methods for addiction research or that show promising future applicability to SUD research; and /or 2. test an innovative and significant hypothesis for which there are scant precedent or preliminary data and which, if confirmed, would transform current thinking.

Eligibility

See official grant page for eligibility requirements

Industry Tags

Healthcare

About This Grant

The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innovative or conceptually creative research related to the etiology, pathophysiology, prevention, or treatment of substance use disorders (SUDs). It supports high-risk and potentially high-impact research that is sparse or not included in NIDA's current portfolio that has the potential to transform SUD research. The proposed research should: 1. develop, and/or adapt, revolutionary techniques or methods for addiction research or that show promising future applicability to SUD research; and /or 2. test an innovative and significant hypothesis for which there are scant precedent or preliminary data and which, if confirmed, would transform current thinking.

Funding Information

Award Ceiling
$150,000
Estimated Total Program Funding
$150,000

Eligibility Overview

This opportunity from National Institutes of Health is open to eligible applicants nationwide. Organizations working in Healthcare are especially encouraged to review the requirements.

Federal grant opportunities like this one are typically open to a range of applicant types. Common eligible organizations include:

  • Nonprofits and 501(c)(3) organizations
  • Small businesses and startups (especially for SBIR/STTR programs)
  • State, local, and tribal governments
  • Colleges, universities, and research institutions
  • Individuals (for select programs in education, arts, and research)

Eligibility requirements vary by opportunity. Always review the official listing before investing time in an application.

How to Apply

  1. 1

    Review the full opportunity

    Read the complete Notice of Funding Opportunity (NOFO) for this National Institutes of Health program on its official page (https://www.grants.gov/search-results-detail/357941).

  2. 2

    Confirm eligibility

    Check that your organization meets every requirement set by National Institutes of Health — applicant type, location, registration status, and any prior-award restrictions.

  3. 3

    Prepare required documents

    Gather your budget narrative, needs statement, organizational details, SAM.gov registration, and any required certifications.

  4. 4

    Submit before the deadline

    This opportunity closes on August 11, 2027. Submit at least 48 hours early — portal systems are often slow near closing time.

Grant Writing Tips

Proposals for healthcare programs such as those from National Institutes of Health are competitive — these tips can strengthen your application:

  • Start your application at least 4 weeks before the deadline — rushed proposals score lower.
  • Tailor your needs statement to match the funder's stated priorities, using their exact language where possible.
  • Have a colleague outside your team review your budget narrative before submitting — fresh eyes catch errors reviewers penalize.

More Grants from National Institutes of Health

Frequently Asked Questions

Who is eligible for Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)?

This opportunity from National Institutes of Health is open to eligible applicants nationwide. Organizations working in Healthcare are especially encouraged to review the requirements. Always confirm the full eligibility criteria on the official listing before applying.

How much funding does Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional) provide?

Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional) provides awards of up to $150,000.

When is the deadline for Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)?

The application deadline for Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional) is August 11, 2027. Submit at least 48 hours early to avoid last-minute portal issues.

How do I apply for Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)?

Apply for Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional) through the official grant page (https://www.grants.gov/search-results-detail/357941). Confirm your eligibility and prepare your application materials before the deadline.

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