Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21)
Description
The World Trade Center (WTC) Health Program supports exploratory and developmental research projects (R21) that address issues related to diagnostic or treatment uncertainty among individuals receiving monitoring and/or treatment under Subtitle C of the James Zadroga 9/11 Health and Compensation Act of 2010, as amended. This R21 Notice of Funding Opportunity (NOFO) is intended to encourage exploratory/developmental research by supporting the early and conceptual stages of project development to assess the feasibility of new areas of investigation with the potential to improve treatment effectiveness and diagnostic practices. These studies may lead to breakthroughs in a particular area or to the development of new interventions, techniques, agents, methodologies, models, or approaches with potential clinical impact. They are expected to break new ground or extend prior discoveries in new directions or applications. Applicants are expected to propose research for which there is likely to be minimal or no preliminary data.
Eligibility
See official grant page for eligibility requirements
Industry Tags
About This Grant
The World Trade Center (WTC) Health Program supports exploratory and developmental research projects (R21) that address issues related to diagnostic or treatment uncertainty among individuals receiving monitoring and/or treatment under Subtitle C of the James Zadroga 9/11 Health and Compensation Act of 2010, as amended. This R21 Notice of Funding Opportunity (NOFO) is intended to encourage exploratory/developmental research by supporting the early and conceptual stages of project development to assess the feasibility of new areas of investigation with the potential to improve treatment effectiveness and diagnostic practices. These studies may lead to breakthroughs in a particular area or to the development of new interventions, techniques, agents, methodologies, models, or approaches with potential clinical impact. They are expected to break new ground or extend prior discoveries in new directions or applications. Applicants are expected to propose research for which there is likely to be minimal or no preliminary data.
Funding Information
- Award Ceiling
- $365,000
- Estimated Total Program Funding
- $18,000,000
- Expected Number of Awards
- 36
Eligibility Overview
This opportunity from Centers for Disease Control and Prevention - ERA is open to eligible applicants nationwide. Organizations working in Federal are especially encouraged to review the requirements.
Federal grant opportunities like this one are typically open to a range of applicant types. Common eligible organizations include:
- Nonprofits and 501(c)(3) organizations
- Small businesses and startups (especially for SBIR/STTR programs)
- State, local, and tribal governments
- Colleges, universities, and research institutions
- Individuals (for select programs in education, arts, and research)
Eligibility requirements vary by opportunity. Always review the official listing before investing time in an application.
How to Apply
- 1
Review the full opportunity
Read the complete Notice of Funding Opportunity (NOFO) for this Centers for Disease Control and Prevention - ERA program on its official page (https://www.grants.gov/search-results-detail/360753).
- 2
Confirm eligibility
Check that your organization meets every requirement set by Centers for Disease Control and Prevention - ERA — applicant type, location, registration status, and any prior-award restrictions.
- 3
Prepare required documents
Gather your budget narrative, needs statement, organizational details, SAM.gov registration, and any required certifications.
- 4
Submit before the deadline
This opportunity closes on December 8, 2026. Submit at least 48 hours early — portal systems are often slow near closing time.
Grant Writing Tips
Proposals for federal programs such as those from Centers for Disease Control and Prevention - ERA are competitive — these tips can strengthen your application:
- ✓Start your application at least 4 weeks before the deadline — rushed proposals score lower.
- ✓Tailor your needs statement to match the funder's stated priorities, using their exact language where possible.
- ✓Have a colleague outside your team review your budget narrative before submitting — fresh eyes catch errors reviewers penalize.
More Grants from Centers for Disease Control and Prevention - ERA
Frequently Asked Questions
Who is eligible for Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21)?
This opportunity from Centers for Disease Control and Prevention - ERA is open to eligible applicants nationwide. Organizations working in Federal are especially encouraged to review the requirements. Always confirm the full eligibility criteria on the official listing before applying.
How much funding does Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21) provide?
Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21) provides awards of up to $365,000.
When is the deadline for Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21)?
The application deadline for Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21) is December 8, 2026. Submit at least 48 hours early to avoid last-minute portal issues.
How do I apply for Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21)?
Apply for Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21) through the official grant page (https://www.grants.gov/search-results-detail/360753). Confirm your eligibility and prepare your application materials before the deadline.
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