Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets)
Description
This program will advance scientific community datasets to enable scientific discovery and innovation using artificial intelligence (AI) and other methods. Its goal is to increase the value that can be derived from existing scientific datasets by leveraging novel methods and artificial intelligence (AI). This will unlock new AI-driven insights. It can enable interdisciplinary research. It also enables investigations outside of the original motivation for data collection and analysis. The program seeks to 1) apply AI-based capabilities to feature extraction and metadata generation, and the integration of multiple datasets. 2) Develop robust data pipelines necessary for automated analysis of existing datasets and similar use-cases by AI tools and systems. 3) Augment and/or harmonize existing datasets to better enable use by AI data pipelines and automated analysis. Proposals should address dataset security and integrity. Governance and the process for scientific communities to contribute to the datasets should also be addressed. Proposals are encouraged to leverage existing resources. These may include NSF data platforms , the NSF Integrated Data Systems and Services program , the NSF-led National AI Research Resource , the Genesis Mission platform , or other national infrastructure. NSF is open to exploring partnerships with philanthropy, private industry, or the non-profit sector to support additional proposals or collaborative opportunities that will advance AI-driven scientific discovery through unlocking the value of high-impact scientific datasets. Expanding Participation in STEM, NSF Priorities, and Gold Standard Science: NSF prioritizes cutting-edge discovery science and engineering research, advancing technology and innovation, and creating opportunities for all Americans. NSF has established priorities set forth by Congress, the administration and the NSF director to promote NSF's mission . Proposers should review the list of NSF priorities and are encouraged to align their proposals with them, where appropriate. NSF also expects the highest standards of scientific rigor, integrity and adherence tenets of Gold Standard Science in proposals, as appropriate for the field of science and research modality.
Eligibility
See official grant page for eligibility requirements
Industry Tags
About This Grant
This program will advance scientific community datasets to enable scientific discovery and innovation using artificial intelligence (AI) and other methods. Its goal is to increase the value that can be derived from existing scientific datasets by leveraging novel methods and artificial intelligence (AI). This will unlock new AI-driven insights. It can enable interdisciplinary research. It also enables investigations outside of the original motivation for data collection and analysis. The program seeks to 1) apply AI-based capabilities to feature extraction and metadata generation, and the integration of multiple datasets. 2) Develop robust data pipelines necessary for automated analysis of existing datasets and similar use-cases by AI tools and systems. 3) Augment and/or harmonize existing datasets to better enable use by AI data pipelines and automated analysis. Proposals should address dataset security and integrity. Governance and the process for scientific communities to contribute to the datasets should also be addressed. Proposals are encouraged to leverage existing resources. These may include NSF data platforms , the NSF Integrated Data Systems and Services program , the NSF-led National AI Research Resource , the Genesis Mission platform , or other national infrastructure. NSF is open to exploring partnerships with philanthropy, private industry, or the non-profit sector to support additional proposals or collaborative opportunities that will advance AI-driven scientific discovery through unlocking the value of high-impact scientific datasets. Expanding Participation in STEM, NSF Priorities, and Gold Standard Science: NSF prioritizes cutting-edge discovery science and engineering research, advancing technology and innovation, and creating opportunities for all Americans. NSF has established priorities set forth by Congress, the administration and the NSF director to promote NSF's mission . Proposers should review the list of NSF priorities and are encouraged to align their proposals with them, where appropriate. NSF also expects the highest standards of scientific rigor, integrity and adherence tenets of Gold Standard Science in proposals, as appropriate for the field of science and research modality.
Funding Information
- Estimated Total Program Funding
- $100,000,000
- Expected Number of Awards
- 50
Eligibility Overview
This opportunity from U.S. National Science Foundation is open to eligible applicants nationwide. Organizations working in Research are especially encouraged to review the requirements.
Federal grant opportunities like this one are typically open to a range of applicant types. Common eligible organizations include:
- Nonprofits and 501(c)(3) organizations
- Small businesses and startups (especially for SBIR/STTR programs)
- State, local, and tribal governments
- Colleges, universities, and research institutions
- Individuals (for select programs in education, arts, and research)
Eligibility requirements vary by opportunity. Always review the official listing before investing time in an application.
How to Apply
- 1
Review the full opportunity
Read the complete Notice of Funding Opportunity (NOFO) for this U.S. National Science Foundation program on its official page (https://www.grants.gov/search-results-detail/363268).
- 2
Confirm eligibility
Check that your organization meets every requirement set by U.S. National Science Foundation — applicant type, location, registration status, and any prior-award restrictions.
- 3
Prepare required documents
Gather your budget narrative, needs statement, organizational details, SAM.gov registration, and any required certifications.
- 4
Submit before the deadline
This opportunity closes on November 4, 2026. Submit at least 48 hours early — portal systems are often slow near closing time.
Grant Writing Tips
Proposals for research programs such as those from U.S. National Science Foundation are competitive — these tips can strengthen your application:
- ✓Start your application at least 4 weeks before the deadline — rushed proposals score lower.
- ✓Tailor your needs statement to match the funder's stated priorities, using their exact language where possible.
- ✓Have a colleague outside your team review your budget narrative before submitting — fresh eyes catch errors reviewers penalize.
More Grants from U.S. National Science Foundation
Frequently Asked Questions
Who is eligible for Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets)?
This opportunity from U.S. National Science Foundation is open to eligible applicants nationwide. Organizations working in Research are especially encouraged to review the requirements. Always confirm the full eligibility criteria on the official listing before applying.
How much funding does Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets) provide?
The total estimated program funding for Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets) is $100,000,000.
When is the deadline for Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets)?
The application deadline for Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets) is November 4, 2026. Submit at least 48 hours early to avoid last-minute portal issues.
How do I apply for Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets)?
Apply for Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets) through the official grant page (https://www.grants.gov/search-results-detail/363268). Confirm your eligibility and prepare your application materials before the deadline.
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