U.S. National Science Foundation State and Regional Artificial Intelligence Infrastructure Hubs:
Description
The NSF State and Regional AI Infrastructure Hubs program aims to expand access to the compute required for AI-enabled scientific discovery and to transform the research, education, and training opportunities offered by institutions of higher education. AI Infrastructure Hubs will connect researchers to new compute infrastructure that leverages contributions from state governments, research institutions, industry, and philanthropy, accelerating AI-enabled discovery across science and engineering and developing a skilled technical workforce for AI use in the scientific enterprise. The program responds to a core tenet of Science: A New Golden Age to renew America’s research and development (R&D) for changes in today’s scientific enterprise, including the role of AI in laying the foundation for a new era of scientific discovery and the growing role of industry and philanthropy in funding R&D. In response, the Administration’s FY28 R&D Priorities Memorandum called for investing in AI for science as a national mission and expanding the scale of, and flexible access to, advanced compute and data infrastructure that researchers now require for frontier scientific discovery. Each AI Infrastructure Hub will be organized as a flexible state or regional consortium of state and local governments, research institutions, philanthropies, and the private sector. Consortia will be responsible for all funding for new or expanded computing, data, and AI resources, whether on-premises or cloud-based. NSF will fund each Hub’s consortium coordination, AI infrastructure workforce development, and faculty training and coursework development in leveraging AI for science.
Eligibility
See official grant page for eligibility requirements
Industry Tags
About This Grant
The NSF State and Regional AI Infrastructure Hubs program aims to expand access to the compute required for AI-enabled scientific discovery and to transform the research, education, and training opportunities offered by institutions of higher education. AI Infrastructure Hubs will connect researchers to new compute infrastructure that leverages contributions from state governments, research institutions, industry, and philanthropy, accelerating AI-enabled discovery across science and engineering and developing a skilled technical workforce for AI use in the scientific enterprise. The program responds to a core tenet of Science: A New Golden Age to renew America’s research and development (R&D) for changes in today’s scientific enterprise, including the role of AI in laying the foundation for a new era of scientific discovery and the growing role of industry and philanthropy in funding R&D. In response, the Administration’s FY28 R&D Priorities Memorandum called for investing in AI for science as a national mission and expanding the scale of, and flexible access to, advanced compute and data infrastructure that researchers now require for frontier scientific discovery. Each AI Infrastructure Hub will be organized as a flexible state or regional consortium of state and local governments, research institutions, philanthropies, and the private sector. Consortia will be responsible for all funding for new or expanded computing, data, and AI resources, whether on-premises or cloud-based. NSF will fund each Hub’s consortium coordination, AI infrastructure workforce development, and faculty training and coursework development in leveraging AI for science.
Funding Information
- Estimated Total Program Funding
- $100,000,000
Eligibility Overview
This opportunity from U.S. National Science Foundation is open to eligible applicants nationwide. Organizations working in Research are especially encouraged to review the requirements.
Federal grant opportunities like this one are typically open to a range of applicant types. Common eligible organizations include:
- Nonprofits and 501(c)(3) organizations
- Small businesses and startups (especially for SBIR/STTR programs)
- State, local, and tribal governments
- Colleges, universities, and research institutions
- Individuals (for select programs in education, arts, and research)
Eligibility requirements vary by opportunity. Always review the official listing before investing time in an application.
How to Apply
- 1
Review the full opportunity
Read the complete Notice of Funding Opportunity (NOFO) for this U.S. National Science Foundation program on its official page (https://www.grants.gov/search-results-detail/363481).
- 2
Confirm eligibility
Check that your organization meets every requirement set by U.S. National Science Foundation — applicant type, location, registration status, and any prior-award restrictions.
- 3
Prepare required documents
Gather your budget narrative, needs statement, organizational details, SAM.gov registration, and any required certifications.
- 4
Submit before the deadline
This opportunity closes on November 4, 2026. Submit at least 48 hours early — portal systems are often slow near closing time.
Grant Writing Tips
Proposals for research programs such as those from U.S. National Science Foundation are competitive — these tips can strengthen your application:
- ✓Start your application at least 4 weeks before the deadline — rushed proposals score lower.
- ✓Tailor your needs statement to match the funder's stated priorities, using their exact language where possible.
- ✓Have a colleague outside your team review your budget narrative before submitting — fresh eyes catch errors reviewers penalize.
More Grants from U.S. National Science Foundation
Frequently Asked Questions
Who is eligible for U.S. National Science Foundation State and Regional Artificial Intelligence Infrastructure Hubs:?
This opportunity from U.S. National Science Foundation is open to eligible applicants nationwide. Organizations working in Research are especially encouraged to review the requirements. Always confirm the full eligibility criteria on the official listing before applying.
How much funding does U.S. National Science Foundation State and Regional Artificial Intelligence Infrastructure Hubs: provide?
The total estimated program funding for U.S. National Science Foundation State and Regional Artificial Intelligence Infrastructure Hubs: is $100,000,000.
When is the deadline for U.S. National Science Foundation State and Regional Artificial Intelligence Infrastructure Hubs:?
The application deadline for U.S. National Science Foundation State and Regional Artificial Intelligence Infrastructure Hubs: is November 4, 2026. Submit at least 48 hours early to avoid last-minute portal issues.
How do I apply for U.S. National Science Foundation State and Regional Artificial Intelligence Infrastructure Hubs:?
Apply for U.S. National Science Foundation State and Regional Artificial Intelligence Infrastructure Hubs: through the official grant page (https://www.grants.gov/search-results-detail/363481). Confirm your eligibility and prepare your application materials before the deadline.
Helpful Resources
Need help writing your grant application?
Try Instrumentl — Grant Writing Software →Starting a nonprofit to apply for grants?
Launch your nonprofit with Swyft Filings →GrantLocate may earn a commission from qualifying purchases. This does not affect our grant listings.